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Redundancy in Antigen-Presenting Function of the HLA-DR and -DQ Molecules in the Multiple Sclerosis-Associated HLA-DR2 Haplotype

The three HLA class II alleles of the DR2 haplotype, DRB1*1501, DRB5*0101, and DQB1*0602, are in strong linkage disequilibrium and confer most of the genetic risk to multiple sclerosis. Functional redundancy in Ag presentation by these class II molecules would allow recognition by a single TCR of id...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Sospedra, Mireia, Muraro, Paolo A., Stefanová, Irena, Zhao, Yingdong, Chung, Katherine, Li, Yili, Giulianotti, Marc, Simon, Richard, Mariuzza, Roy, Pinilla, Clemencia, Martin, Roland
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2006
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2746197/
https://ncbi.nlm.nih.gov/pubmed/16424227
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