CHCHD2 inhibits apoptosis by interacting with Bcl-x L to regulate Bax activation

Mitochondrial outer membrane permeabilization (MOMP) is a critical control point during apoptosis that results in the release of pro-apoptotic mitochondrial contents such as cytochrome c. MOMP is largely controlled by Bcl-2 family proteins such as Bax, which under various apoptotic stresses becomes...

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Bibliographische Detailangaben
Veröffentlicht in:Cell Death Differ
Hauptverfasser: Liu, Y, Clegg, H V, Leslie, P L, Di, J, Tollini, L A, He, Y, Kim, T-H, Jin, A, Graves, L M, Zheng, J, Zhang, Y
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2015
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Original Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4423185/
https://ncbi.nlm.nih.gov/pubmed/25476776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2014.194
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