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PUMA Promotes Bax Translocation by Both Directly Interacting with Bax and by Competitive Binding to Bcl-X(L) during UV-induced Apoptosis

Cell apoptosis induced by UV irradiation is a highly complex process in which different molecular signaling pathways are involved. p53 up-regulated modulator of apoptosis (PUMA) has been proposed as an important regulator in UV irradiation-induced apoptosis. However, the molecular mechanism through...

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Detalhes bibliográficos
Main Authors: Zhang, Yingjie, Xing, Da, Liu, Lei
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2704159/
https://ncbi.nlm.nih.gov/pubmed/19439449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E08-11-1109
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