Age and sun exposure-related widespread genomic blocks of hypomethylation in nonmalignant skin

BACKGROUND: Aging and sun exposure are the leading causes of skin cancer. It has been shown that epigenetic changes, such as DNA methylation, are well established mechanisms for cancer, and also have emerging roles in aging and common disease. Here, we directly ask whether DNA methylation is altered...

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Vydáno v:Genome Biol
Hlavní autoři: Vandiver, Amy R, Irizarry, Rafael A, Hansen, Kasper D, Garza, Luis A, Runarsson, Arni, Li, Xin, Chien, Anna L, Wang, Timothy S, Leung, Sherry G, Kang, Sewon, Feinberg, Andrew P
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2015
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4423110/
https://ncbi.nlm.nih.gov/pubmed/25886480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-015-0644-y
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