Large-scale hypomethylated blocks associated with Epstein-Barr virus–induced B-cell immortalization

Altered DNA methylation occurs ubiquitously in human cancer from the earliest measurable stages. A cogent approach to understanding the mechanism and timing of altered DNA methylation is to analyze it in the context of carcinogenesis by a defined agent. Epstein-Barr virus (EBV) is a human oncogenic...

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Detalhes bibliográficos
Main Authors: Hansen, Kasper D., Sabunciyan, Sarven, Langmead, Ben, Nagy, Noemi, Curley, Rebecca, Klein, Georg, Klein, Eva, Salamon, Daniel, Feinberg, Andrew P.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3912409/
https://ncbi.nlm.nih.gov/pubmed/24068705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.157743.113
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