Variation in Glucose Homeostasis Traits Associated With P2RX7 Polymorphisms in Mice and Humans

CONTEXT: Extracellular nucleotide receptors are expressed in pancreatic B-cells. Purinergic signaling via these receptors may regulate pancreatic B-cell function. OBJECTIVE: We hypothesized that purinergic signaling might influence glucose regulation and sought evidence in human studies of glycemic...

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Detalhes bibliográficos
Publicado no:J Clin Endocrinol Metab
Main Authors: Todd, Jennifer N., Poon, Wenny, Lyssenko, Valeriya, Groop, Leif, Nichols, Brendan, Wilmot, Michael, Robson, Simon, Enjyoji, Keiichi, Herman, Mark A., Hu, Cheng, Zhang, Rong, Jia, Weiping, Ma, Ronald, Florez, Jose C., Friedman, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2015
Assuntos:
Hot Topics in Translational Endocrinology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4422893/
https://ncbi.nlm.nih.gov/pubmed/25719930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2014-4160
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