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Variants in the FFAR1 Gene Are Associated with Beta Cell Function
BACKGROUND: The FFAR1 receptor is expressed mainly in pancreatic beta cells and is activated by medium to long chain free fatty acids (FFAs), as well as by thiazolidinediones, resulting in elevated Ca(2+) concentrations and promotion of insulin secretion. These properties suggest that FFAR1 could be...
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| Main Authors: | , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Public Library of Science
2007
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2042513/ https://ncbi.nlm.nih.gov/pubmed/17987108 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001090 |
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