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Prioritizing genes for follow-up from genome wide association studies using information on gene expression in tissues relevant for type 2 diabetes mellitus

BACKGROUND: Genome-wide association studies (GWAS) have emerged as a powerful approach for identifying susceptibility loci associated with polygenetic diseases such as type 2 diabetes mellitus (T2DM). However, it is still a daunting task to prioritize single nucleotide polymorphisms (SNPs) from GWAS...

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Detalhes bibliográficos
Main Authors: Parikh, Hemang, Lyssenko, Valeriya, Groop, Leif C
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2815699/
https://ncbi.nlm.nih.gov/pubmed/20043853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-8794-2-72
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