Wird geladen...

PERK Limits Drosophila Lifespan by Promoting Intestinal Stem Cell Proliferation in Response to ER Stress

Intestinal homeostasis requires precise control of intestinal stem cell (ISC) proliferation. In Drosophila, this control declines with age largely due to chronic activation of stress signaling and associated chronic inflammatory conditions. An important contributor to this condition is the age-assoc...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:PLoS Genet
Hauptverfasser: Wang, Lifen, Ryoo, Hyung Don, Qi, Yanyan, Jasper, Heinrich
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4422665/
https://ncbi.nlm.nih.gov/pubmed/25945494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005220
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!