Identification of NF-κB and PLCL2 as new susceptibility genes and highlights on a potential role of IRF8 through interferon signature modulation in systemic sclerosis

INTRODUCTION: Systemic sclerosis (SSc) and primary biliary cirrhosis (PBC) are rare polygenic autoimmune diseases (AIDs) characterized by fibroblast dysfunction. Furthermore, both diseases share some genetic bases with other AIDs, as evidenced by autoimmune gene pleiotropism. The present study was u...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Arthritis Res Ther
Main Authors: Arismendi, Maria, Giraud, Matthieu, Ruzehaji, Nadira, Dieudé, Philippe, Koumakis, Eugenie, Ruiz, Barbara, Airo, Paolo, Cusi, Daniele, Matucci-Cerinic, Marco, Salvi, Erika, Cuomo, Giovanna, Hachulla, Eric, Diot, Elisabeth, Caramaschi, Paola, Riccieri, Valeria, Avouac, Jérôme, Kayser, Cristiane, Allanore, Yannick
פורמט: Artigo
שפה:Inglês
יצא לאור: BioMed Central 2015
נושאים:
Research Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4422604/
https://ncbi.nlm.nih.gov/pubmed/25880423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-015-0572-y
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