Identification of NF-κB and PLCL2 as new susceptibility genes and highlights on a potential role of IRF8 through interferon signature modulation in systemic sclerosis

INTRODUCTION: Systemic sclerosis (SSc) and primary biliary cirrhosis (PBC) are rare polygenic autoimmune diseases (AIDs) characterized by fibroblast dysfunction. Furthermore, both diseases share some genetic bases with other AIDs, as evidenced by autoimmune gene pleiotropism. The present study was u...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Arthritis Res Ther
Autores principales: Arismendi, Maria, Giraud, Matthieu, Ruzehaji, Nadira, Dieudé, Philippe, Koumakis, Eugenie, Ruiz, Barbara, Airo, Paolo, Cusi, Daniele, Matucci-Cerinic, Marco, Salvi, Erika, Cuomo, Giovanna, Hachulla, Eric, Diot, Elisabeth, Caramaschi, Paola, Riccieri, Valeria, Avouac, Jérôme, Kayser, Cristiane, Allanore, Yannick
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4422604/
https://ncbi.nlm.nih.gov/pubmed/25880423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-015-0572-y
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares