Population-Based in Vitro Hazard and Concentration–Response Assessment of Chemicals: The 1000 Genomes High-Throughput Screening Study

Background: Understanding of human variation in toxicity to environmental chemicals remains limited, so human health risk assessments still largely rely on a generic 10-fold factor (10(½) each for toxicokinetics and toxicodynamics) to account for sensitive individuals or subpopulations. Objectives:...

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Udgivet i:Environ Health Perspect
Main Authors: Abdo, Nour, Xia, Menghang, Brown, Chad C., Kosyk, Oksana, Huang, Ruili, Sakamuru, Srilatha, Zhou, Yi-Hui, Jack, John R., Gallins, Paul, Xia, Kai, Li, Yun, Chiu, Weihsueh A., Motsinger-Reif, Alison A., Austin, Christopher P., Tice, Raymond R., Rusyn, Ivan, Wright, Fred A.
Format: Artigo
Sprog:Inglês
Udgivet: NLM-Export 2015
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4421772/
https://ncbi.nlm.nih.gov/pubmed/25622337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/ehp.1408775
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