Quantitative High-Throughput Screening for Chemical Toxicity in a Population-Based In Vitro Model

A shift in toxicity testing from in vivo to in vitro may efficiently prioritize compounds, reveal new mechanisms, and enable predictive modeling. Quantitative high-throughput screening (qHTS) is a major source of data for computational toxicology, and our goal in this study was to aid in the develop...

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Autori principali: Lock, Eric F., Abdo, Nour, Huang, Ruili, Xia, Menghang, Kosyk, Oksana, O’Shea, Shannon H., Zhou, Yi-Hui, Sedykh, Alexander, Tropsha, Alexander, Austin, Christopher P., Tice, Raymond R., Wright, Fred A., Rusyn, Ivan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2012
Soggetti:
Systems Toxicology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3307611/
https://ncbi.nlm.nih.gov/pubmed/22268004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfs023
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