SNP Discovery in Pooled Samples With Mismatch Repair Detection

A targeted discovery effort is required to identify low frequency single nucleotide polymorphisms (SNPs) in human coding and regulatory regions. We here describe combining mismatch repair detection (MRD) with dideoxy terminator sequencing to detect SNPs in pooled DNA samples. MRD enriches for varian...

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Bibliografiska uppgifter
I publikationen:Genome Res
Huvudupphovsmän: Fakhrai-Rad, Hossein, Zheng, Jianbiao, Willis, Thomas D., Wong, Kee, Suyenaga, Kent, Moorhead, Martin, Eberle, Jim, Thorstenson, Yvonne R., Jones, Ted, Davis, Ronald W., Namsaraev, Eugeni, Faham, Malek
Materialtyp: Artigo
Språk:Inglês
Publicerad: Cold Spring Harbor Laboratory Press 2004
Ämnen:
Methods
Länkar:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC442157/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15231755/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gr.2373904
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