Expression levels of MHC class I molecules are inversely correlated with promiscuity of peptide binding

Highly polymorphic major histocompatibility complex (MHC) molecules are at the heart of adaptive immune responses, playing crucial roles in many kinds of disease and in vaccination. We report that breadth of peptide presentation and level of cell surface expression of class I molecules are inversely...

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Detaylı Bibliyografya
Yayımlandı:eLife
Asıl Yazarlar: Chappell, Paul E, Meziane, El Kahina, Harrison, Michael, Magiera, Łukasz, Hermann, Clemens, Mears, Laura, Wrobel, Antoni G, Durant, Charlotte, Nielsen, Lise Lotte, Buus, Søren, Ternette, Nicola, Mwangi, William, Butter, Colin, Nair, Venugopal, Ahyee, Trudy, Duggleby, Richard, Madrigal, Alejandro, Roversi, Pietro, Lea, Susan M, Kaufman, Jim
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: eLife Sciences Publications, Ltd 2015
Konular:
Immunology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4420994/
https://ncbi.nlm.nih.gov/pubmed/25860507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.05345
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