Modulation of Macrophage Gene Expression via Liver X Receptor α Serine 198 Phosphorylation

In mouse models of atherosclerosis, normalization of hyperlipidemia promotes macrophage emigration and regression of atherosclerotic plaques in part by liver X receptor (LXR)-mediated induction of the chemokine receptor CCR7. Here we report that LXRα serine 198 (S198) phosphorylation modulates CCR7...

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Bibliografiska uppgifter
I publikationen:Mol Cell Biol
Huvudupphovsmän: Wu, Chaowei, Hussein, Maryem A., Shrestha, Elina, Leone, Sarah, Aiyegbo, Mohammed S., Lambert, W. Marcus, Pourcet, Benoit, Cardozo, Timothy, Gustafson, Jan-Ake, Fisher, Edward A., Pineda-Torra, Ines, Garabedian, Michael J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2015
Ämnen:
Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4420924/
https://ncbi.nlm.nih.gov/pubmed/25825525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00985-14
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