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Solution Structure of the Reduced Form of Human Peroxiredoxin-6 Elucidated Using Zero-Length Chemical Cross-linking And Homology Modeling()
Peroxiredoxin-6 (PRDX6) is an unusual member of the peroxiredoxin family of antioxidant enzymes that has only one evolutionarily conserved cysteine. It reduces oxidized lipids and ROS by oxidation of the active site cysteine (Cys-47) to a sulfenic acid, but the mechanism for conversion back to a sul...
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| Publicado no: | Biochem J |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4420655/ https://ncbi.nlm.nih.gov/pubmed/25748205 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20141463 |
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