Pharmacological inhibition of ALDH1A in mice decreases all-trans retinoic acid concentrations in a tissue specific manner

all-trans retinoic acid (atRA), the active metabolite of vitamin A, is an essential signaling molecule. Specifically the concentrations of atRA are spatiotemporally controlled in target tissues such as the liver and the testes. While the enzymes of the aldehyde dehydrogenase 1A family (ALDH1A) are b...

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Bibliografiset tiedot
Julkaisussa:Biochem Pharmacol
Päätekijät: Arnold, Samuel L. M., Kent, Travis, Hogarth, Cathryn A., Griswold, Michael D., Amory, John K., Isoherranen, Nina
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2015
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4420653/
https://ncbi.nlm.nih.gov/pubmed/25764981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2015.03.001
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