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Energetic evaluation of binding modes in the C3d and Factor H (CCP 19-20) complex

As a part of innate immunity, the complement system relies on activation of the alternative pathway (AP). While feed-forward amplification generates an immune response towards foreign surfaces, the process requires regulation to prevent an immune response on the surface of host cells. Factor H (FH)...

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Bibliografiske detaljer
Udgivet i:Protein Sci
Main Authors: E S Harrison, Reed, Gorham, Ronald D, Morikis, Dimitrios
Format: Artigo
Sprog:Inglês
Udgivet: BlackWell Publishing Ltd 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4420527/
https://ncbi.nlm.nih.gov/pubmed/25628052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2650
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