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Molecular Mechanisms of Macular Degeneration Associated with the Complement Factor H Y402H Mutation
A single nucleotide polymorphism, tyrosine at position 402 to histidine (Y402H), within the gene encoding complement factor H (FH) predisposes individuals to acquiring age-related macular degeneration (AMD) after aging. This polymorphism occurs in short consensus repeat (SCR) 7 of FH and results in...
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| Publicado no: | Biophys J |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6350009/ https://ncbi.nlm.nih.gov/pubmed/30616835 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2018.12.007 |
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