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Hydrogen exchange of disordered proteins in Escherichia coli

A truly disordered protein lacks a stable fold and its backbone amide protons exchange with solvent at rates predicted from studies of unstructured peptides. We have measured the exchange rates of two model disordered proteins, FlgM and α-synuclein, in buffer and in Escherichia coli using the NMR ex...

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Detaylı Bibliyografya
Yayımlandı:Protein Sci
Asıl Yazarlar: Smith, Austin E, Zhou, Larry Z, Pielak, Gary J
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BlackWell Publishing Ltd 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4420520/
https://ncbi.nlm.nih.gov/pubmed/25611326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2643
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