Reversal of hemochromatosis by apotransferrin in non-transfused and transfused Hbb(th3/+) (heterozygous b1/b2 globin gene deletion) mice

Intermediate beta-thalassemia has a broad spectrum of sequelae and affected subjects may require occasional blood transfusions over their lifetime to correct anemia. Iron overload in intermediate beta-thalassemia results from a paradoxical intestinal absorption, iron release from macrophages and hep...

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Bibliografiske detaljer
Udgivet i:	Haematologica
Main Authors:	Gelderman, Monique P., Baek, Jin Hyen, Yalamanoglu, Ayla, Puglia, Michele, Vallelian, Florence, Burla, Bo, Vostal, Jaroslav, Schaer, Dominik J., Buehler, Paul W.
Format:	Artigo
Sprog:	Inglês
Udgivet:	Ferrata Storti Foundation 2015
Fag:	Articles
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC4420210/ https://ncbi.nlm.nih.gov/pubmed/25616571 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2014.117325
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Reversal of hemochromatosis by apotransferrin in non-transfused and transfused Hbb(th3/+) (heterozygous b1/b2 globin gene deletion) mice

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