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BRAF Mutation in Hairy Cell Leukemia
BRAF is a serine/threonine kinase with a regulatory role in the mitogen-activated protein kinase (MAPK) signaling pathway. A mutation in the RAF gene, especially in BRAF protein, leads to an increased stimulation of this cascade, causing uncontrolled cell division and development of malignancy. Seve...
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| 出版年: | Oncol Rev |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
PAGEPress Publications, Pavia, Italy
2014
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4419648/ https://ncbi.nlm.nih.gov/pubmed/25992240 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4081/oncol.2014.253 |
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