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BRAF Mutation in Hairy Cell Leukemia

BRAF is a serine/threonine kinase with a regulatory role in the mitogen-activated protein kinase (MAPK) signaling pathway. A mutation in the RAF gene, especially in BRAF protein, leads to an increased stimulation of this cascade, causing uncontrolled cell division and development of malignancy. Seve...

詳細記述

保存先:
書誌詳細
出版年:Oncol Rev
主要な著者: Ahmadzadeh, Ahmad, Shahrabi, Saeid, Jaseb, Kaveh, Norozi, Fatemeh, Shahjahani, Mohammad, Vosoughi, Tina, Hajizamani, Saeideh, Saki, Najmaldin
フォーマット: Artigo
言語:Inglês
出版事項: PAGEPress Publications, Pavia, Italy 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4419648/
https://ncbi.nlm.nih.gov/pubmed/25992240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4081/oncol.2014.253
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