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The Role of HDACs as Leukemia Therapy Targets using HDI
Histone deacetylases (HDACs) are the enzymes causing deacetylation of histone and non-histone substrates. Histone deacetylase inhibitors (HDIs) are a family of drugs eliminating the effect of HDACs in malignant cells via inhibition of HDACs. Due to extensive effects upon gene expression through inte...
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| Publicado no: | Int J Hematol Oncol Stem Cell Res |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Tehran University of Medical Sciences, Hematology-Oncology and Stem Cell Transplantation Research Center
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4748691/ https://ncbi.nlm.nih.gov/pubmed/26865932 |
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