BRAF Mutation in Hairy Cell Leukemia

BRAF is a serine/threonine kinase with a regulatory role in the mitogen-activated protein kinase (MAPK) signaling pathway. A mutation in the RAF gene, especially in BRAF protein, leads to an increased stimulation of this cascade, causing uncontrolled cell division and development of malignancy. Seve...

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Enregistré dans:
Détails bibliographiques
Publié dans:Oncol Rev
Auteurs principaux: Ahmadzadeh, Ahmad, Shahrabi, Saeid, Jaseb, Kaveh, Norozi, Fatemeh, Shahjahani, Mohammad, Vosoughi, Tina, Hajizamani, Saeideh, Saki, Najmaldin
Format: Artigo
Langue:Inglês
Publié: PAGEPress Publications, Pavia, Italy 2014
Sujets:
Review
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4419648/
https://ncbi.nlm.nih.gov/pubmed/25992240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4081/oncol.2014.253
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