Establishment of patient-derived xenograft models and cell lines for malignancies of the upper gastrointestinal tract

BACKGROUND: The upper gastrointestinal tract is home to some of most notorious cancers like esophagogastric and pancreatic cancer. Several factors contribute to the lethality of these tumors, but one that stands out for both tumor types is the strong inter- as well as intratumor heterogeneity. Unfor...

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Detalhes bibliográficos
Publicado no:J Transl Med
Main Authors: Damhofer, Helene, Ebbing, Eva A, Steins, Anne, Welling, Lieke, Tol, Johanna A, Krishnadath, Kausilia K, van Leusden, Tom, van de Vijver, Marc J, Besselink, Marc G, Busch, Olivier R, Henegouwen, Mark I van Berge, van Delden, Otto, Meijer, Sybren L, Dijk, Frederike, Medema, Jan Paul, van Laarhoven, Hanneke W, Bijlsma, Maarten F
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4419410/
https://ncbi.nlm.nih.gov/pubmed/25884700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-015-0469-1
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