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Strong foreign promoters contribute to innate inflammatory responses induced by adenovirus transducing vectors
E1-deleted adenovirus (FG Ad) transducing vectors are limited for use in vivo by their induction of strong innate and adaptive inflammatory responses. We have examined the contribution of the transgene cassette, particularly the foreign promoter driving transgene expression, in the induction of inna...
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| 出版年: | Virology |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4419336/ https://ncbi.nlm.nih.gov/pubmed/21255815 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2010.12.054 |
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