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Multiple Innate Immune Pathways Contribute to the Immunogenicity of Recombinant Adenovirus Vaccine Vectors

The innate immune pathways that contribute to the potent immunogenicity of recombinant adenovirus (rAd) vaccine vectors remain largely undefined. Previous studies assessing innate immunity triggered by vaccine vectors have largely focused on in vitro studies involving antigen-presenting cells and on...

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Detalhes bibliográficos
Main Authors: Rhee, Elizabeth G., Blattman, Joseph N., Kasturi, Sudhir P., Kelley, R. Phelps, Kaufman, David R., Lynch, Diana M., La Porte, Annalena, Simmons, Nathaniel L., Clark, Sarah L., Pulendran, Bali, Greenberg, Philip D., Barouch, Dan H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3014160/
https://ncbi.nlm.nih.gov/pubmed/20962088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01597-10
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