Multiple Innate Immune Pathways Contribute to the Immunogenicity of Recombinant Adenovirus Vaccine Vectors

The innate immune pathways that contribute to the potent immunogenicity of recombinant adenovirus (rAd) vaccine vectors remain largely undefined. Previous studies assessing innate immunity triggered by vaccine vectors have largely focused on in vitro studies involving antigen-presenting cells and on...

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Main Authors: Rhee, Elizabeth G., Blattman, Joseph N., Kasturi, Sudhir P., Kelley, R. Phelps, Kaufman, David R., Lynch, Diana M., La Porte, Annalena, Simmons, Nathaniel L., Clark, Sarah L., Pulendran, Bali, Greenberg, Philip D., Barouch, Dan H.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology (ASM) 2011
主題:
Pathogenesis and Immunity
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3014160/
https://ncbi.nlm.nih.gov/pubmed/20962088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01597-10
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