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Strong foreign promoters contribute to innate inflammatory responses induced by adenovirus transducing vectors
E1-deleted adenovirus (FG Ad) transducing vectors are limited for use in vivo by their induction of strong innate and adaptive inflammatory responses. We have examined the contribution of the transgene cassette, particularly the foreign promoter driving transgene expression, in the induction of inna...
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| Publicado no: | Virology |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4419336/ https://ncbi.nlm.nih.gov/pubmed/21255815 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2010.12.054 |
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