Induced transcription and stability of CELF2 mRNA drives widespread alternative splicing during T-cell signaling

Studies in several cell types have highlighted dramatic and diverse changes in mRNA processing that occur upon cellular stimulation. However, the mechanisms and pathways that lead to regulated changes in mRNA processing remain poorly understood. Here we demonstrate that expression of the splicing fa...

Full description

Saved in:
Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Mallory, Michael J., Allon, Samuel J., Qiu, Jinsong, Gazzara, Matthew R., Tapescu, Iulia, Martinez, Nicole M., Fu, Xiang-Dong, Lynch, Kristen W.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2015
Subjects:
PNAS Plus
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4418860/
https://ncbi.nlm.nih.gov/pubmed/25870297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1423695112
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items