Induced transcription and stability of CELF2 mRNA drives widespread alternative splicing during T-cell signaling

Studies in several cell types have highlighted dramatic and diverse changes in mRNA processing that occur upon cellular stimulation. However, the mechanisms and pathways that lead to regulated changes in mRNA processing remain poorly understood. Here we demonstrate that expression of the splicing fa...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Mallory, Michael J., Allon, Samuel J., Qiu, Jinsong, Gazzara, Matthew R., Tapescu, Iulia, Martinez, Nicole M., Fu, Xiang-Dong, Lynch, Kristen W.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2015
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PNAS Plus
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4418860/
https://ncbi.nlm.nih.gov/pubmed/25870297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1423695112
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