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A Synthetic Lethal Screen Identifies a Role for Lin-44/Wnt in C. elegans Embryogenesis
BACKGROUND: The C. elegans proteins PTP-3/LAR-RPTP and SDN-1/Syndecan are conserved cell adhesion molecules. Loss-of-function (LOF) mutations in either ptp-3 or sdn-1 result in low penetrance embryonic developmental defects. Work from other systems has shown that syndecans can function as ligands fo...
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| Publicado no: | PLoS One |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4418752/ https://ncbi.nlm.nih.gov/pubmed/25938228 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0121397 |
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