Učitavanje...
Differential regulation of PTEN by TCR, Akt and FoxO1 controls CD4(+) T cell fate decisions()
Signaling via the Akt/mTOR pathway influences CD4(+) T cell differentiation; low levels favor Treg induction and high levels favor Th induction. Although the lipid phosphatase PTEN suppresses Akt activity the control of PTEN activity is poorly studied in T cells. Here, we identify multiple mechanism...
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| Izdano u: | J Immunol |
|---|---|
| Glavni autori: | , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2015
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4418530/ https://ncbi.nlm.nih.gov/pubmed/25855357 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1402554 |
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