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Vinculin-dependent actin bundling regulates cell migration and traction forces
Vinculin binding to actin filaments is thought to be critical for force transduction within a cell, but direct experimental evidence to support this conclusion has been limited . In this study, we found mutation (R1049E) of the vinculin tail impairs its ability to bind F-actin, stimulate actin polym...
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| 出版年: | Biochem J |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4418518/ https://ncbi.nlm.nih.gov/pubmed/25358683 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20140872 |
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