Vinculin Nucleates Actin Polymerization and Modifies Actin Filament Structure

Vinculin links integrins to the actin cytoskeleton by binding F-actin. Little is known with respect to how this interaction occurs or affects actin dynamics. Here we assess the consequence of the vinculin tail (VT) on actin dynamics by examining its binding to monomeric and filamentous yeast actins....

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Bibliografiske detaljer
Main Authors: Wen, Kuo-Kuang, Rubenstein, Peter A., DeMali, Kris A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2009
Fag:
Molecular Basis of Cell and Developmental Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2781601/
https://ncbi.nlm.nih.gov/pubmed/19736312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.021295
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