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Vinculin Nucleates Actin Polymerization and Modifies Actin Filament Structure

Vinculin links integrins to the actin cytoskeleton by binding F-actin. Little is known with respect to how this interaction occurs or affects actin dynamics. Here we assess the consequence of the vinculin tail (VT) on actin dynamics by examining its binding to monomeric and filamentous yeast actins....

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Detalhes bibliográficos
Main Authors: Wen, Kuo-Kuang, Rubenstein, Peter A., DeMali, Kris A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2781601/
https://ncbi.nlm.nih.gov/pubmed/19736312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.021295
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