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α-Catenin Uses a Novel Mechanism to Activate Vinculin
Vinculin, an actin-binding protein, is emerging as an important regulator of adherens junctions. In focal-adhesions, vinculin is activated by simultaneous binding of talin to its head domain and actin filaments to its tail domain. Talin is not present in adherens junctions. Consequently, the identit...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Biochemistry and Molecular Biology
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3293531/ https://ncbi.nlm.nih.gov/pubmed/22235119 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.297481 |
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