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SHP-2 is activated in response to force on E-cadherin and dephosphorylates vinculin Y822

The response of cells to mechanical inputs is a key determinant of cell behavior. In response to external forces, E-cadherin initiates signal transduction cascades that allow the cell to modulate its contractility to withstand the force. Much attention has focused on identifying the E-cadherin signa...

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Bibliografski detalji
Izdano u:J Cell Sci
Glavni autori: Campbell, Hannah, Heidema, Christy, Pilarczyk, Daisy G., DeMali, Kris A.
Format: Artigo
Jezik:Inglês
Izdano: The Company of Biologists Ltd 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6307880/
https://ncbi.nlm.nih.gov/pubmed/30478196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.216648
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