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CXCR4 blockade induces atherosclerosis by affecting neutrophil function

AIMS: The SDF-1α/CXCR4 dyad was previously shown by us and others to be instrumental in intimal hyperplasia as well as early stage atherosclerosis. We here sought to investigate its impact on clinically relevant stages of atherosclerosis in mouse and man. METHODS AND RESULTS: Immunohistochemical ana...

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Detalhes bibliográficos
Publicado no:J Mol Cell Cardiol
Main Authors: Bot, Ilze, Daissormont, Isabelle T.M.N., Zernecke, Alma, van Puijvelde, Gijs H.M., Kramp, Birgit, de Jager, Saskia C.A., Sluimer, Judith C., Manca, Marco, Hérias, Veronica, Westra, Marijke M., Bot, Martine, van Santbrink, Peter J., van Berkel, Theo J.C., Su, Lishan, Skjelland, Mona, Gullestad, Lars, Kuiper, Johan, Halvorsen, Bente, Aukrust, Paul, Koenen, Rory R., Weber, Christian, Biessen, Erik A.L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4418455/
https://ncbi.nlm.nih.gov/pubmed/24816217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2014.04.021
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