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Pharmacokinetics of the Dual Melatonin Receptor Agonist Tasimelteon in Subjects With Hepatic or Renal Impairment
Tasimelteon is a circadian regulator that resets the master clock in the suprachiasmatic nuclei of the hypothalamus by binding to both melatonin MT(1) and MT(2) receptors making it a dual melatonin receptor agonist. Tasimelteon has been approved by the United States Food and Drug Administration for...
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| Publicado en: | J Clin Pharmacol |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Blackwell Publishing Ltd
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4418347/ https://ncbi.nlm.nih.gov/pubmed/25450415 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcph.440 |
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