A carregar...
The identification of nonpeptide neurotensin receptor partial agonists from the potent antagonist SR48692 using a calcium mobilization assay
In a search for nonpeptide agonists for the neurotensin receptor (NTR1), we replaced the adamantyl amino acid moiety found in the antagonist SR48692 (1a) with leucine and related α-alkylamino acids found in peptide agonists. When tested in a calcium mobilization assay, we found that both d- and l-le...
Na minha lista:
| Publicado no: | Bioorg Med Chem Lett |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4418176/ https://ncbi.nlm.nih.gov/pubmed/19195889 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2009.01.024 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|