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Blockade of mast cell histamine secretion in response to neurotensin by SR 48692, a nonpeptide antagonist of the neurotensin brain receptor.

1. Pretreatment of rat isolated mast cells with SR 48692, a nonpeptide antagonist of the neurotensin (NT) receptor, prevented histamine secretion in response to NT. 2. This inhibition was rapid in onset (approximately 1 min) and dependent upon the concentration of SR 48692 (IC50 approximately 1-10 n...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Miller, L A, Cochrane, D E, Carraway, R E, Feldberg, R S
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1995
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1510300/
https://ncbi.nlm.nih.gov/pubmed/7541694
Etiketak: Etiketa erantsi
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