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Recycled interleukin-7 can be delivered to neighboring T cells

Interleukin-7 (IL-7) is a key homeostatic cytokine that provides signals for T cell survival and proliferation in vivo. Here, we provide evidence that IL-7 utilization is enhanced by a novel mechanism of cytokine “recycling” during which T cells treated with rIL-7 are rapidly induced to express P-ST...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Bazdar, Douglas A., Kalinowska, Magdalena, Panigrahi, Soumya, Sieg, Scott F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4417450/
https://ncbi.nlm.nih.gov/pubmed/25870237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1400560
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