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Decreased IL-7 responsiveness is related to oxidative stress in HIV disease.

HIV disease results in decreased IL-7 receptor expression and IL-7 responsiveness in T cells. To explore mechanisms of these deficiencies, we compared CD127 expression and IL-7 induction of P-STAT5 in T cells from HIV-infected persons with serum concentrations of cytokines (IL-7, IL-6 and IL-15), ma...

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Detalhes bibliográficos
Main Authors: Magdalina Kalinowska, Douglas A Bazdar, Michael M Lederman, Nicholas Funderburg, Scott F Sieg
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2013-01-01
Colecção:PLoS ONE
Acesso em linha:http://europepmc.org/articles/PMC3591367?pdf=render
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