Fenretinide Perturbs Focal Adhesion Kinase in Premalignant and Malignant Human Oral Keratinocytes. Fenretinide’s chemopreventive mechanisms include ECM interactions

The membrane-associated protein, focal adhesion kinase (FAK), modulates cell-extracellular matrix interactions and also conveys pro-survival and proliferative signals. Notably, increased intraepithelial FAK levels accompany transformation of premalignant oral intraepithelial neoplasia (OIN) to oral...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Cancer Prev Res (Phila)
Päätekijät: Han, Byungdo B., Li, Suyang, Tong, Meng, Holpuch, Andrew S., Spinney, Richard, Wang, Daren, Border, Michael B., Liu, Zhongfa, Sarode, Sachin, Pei, Ping, Schwendeman, Steven, Mallery, Susan R.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2015
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4417376/
https://ncbi.nlm.nih.gov/pubmed/25712051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-14-0418
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