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Development and In Vitro-In Vivo Evaluation of Fenretinide-Loaded Oral Mucoadhesive Patches for Site-Specific Chemoprevention of Oral Cancer

PURPOSE: To develop fenretinide oral mucoadhesive patch formulations and evaluate their in vitro and in vivo release performance for future site-specific chemoprevention of oral cancer. METHODS: Solubilization of fenretinide in simulated saliva (SS) was studied by incorporating nonionic surfactants...

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Detalhes bibliográficos
Main Authors: Desai, Kashappa-Goud H., Mallery, Susan R., Holpuch, Andrew S., Schwendeman, Steven P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3171589/
https://ncbi.nlm.nih.gov/pubmed/21674264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-011-0489-3
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