Dietary supplementation with arachidonic acid increases arachidonic acid content in paw, but does not affect arthritis severity or prostaglandin E(2) content in rat adjuvant-induced arthritis model

BACKGROUND: Arachidonic acid (ARA) is an essential fatty acid and a major constituent of biomembranes. It is converted into various lipid mediators, such as prostaglandin E(2) (PGE(2)), which is involved in the development of rheumatoid arthritis (RA). However, the effects of dietary ARA on RA are u...

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Bibliografiske detaljer
Udgivet i:Lipids Health Dis
Main Authors: Tateishi, Norifumi, Kaneda, Yoshihisa, Kakutani, Saki, Kawashima, Hiroshi, Shibata, Hiroshi, Morita, Ikuo
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2015
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4417218/
https://ncbi.nlm.nih.gov/pubmed/25595700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-511X-14-3
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