Dietary supplementation with arachidonic acid increases arachidonic acid content in paw, but does not affect arthritis severity or prostaglandin E(2) content in rat adjuvant-induced arthritis model

BACKGROUND: Arachidonic acid (ARA) is an essential fatty acid and a major constituent of biomembranes. It is converted into various lipid mediators, such as prostaglandin E(2) (PGE(2)), which is involved in the development of rheumatoid arthritis (RA). However, the effects of dietary ARA on RA are u...

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Veröffentlicht in:Lipids Health Dis
Hauptverfasser: Tateishi, Norifumi, Kaneda, Yoshihisa, Kakutani, Saki, Kawashima, Hiroshi, Shibata, Hiroshi, Morita, Ikuo
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2015
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4417218/
https://ncbi.nlm.nih.gov/pubmed/25595700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-511X-14-3
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