The hexameric structure of the human mitochondrial replicative helicase Twinkle

The mitochondrial replicative helicase Twinkle is involved in strand separation at the replication fork of mitochondrial DNA (mtDNA). Twinkle malfunction is associated with rare diseases that include late onset mitochondrial myopathies, neuromuscular disorders and fatal infantile mtDNA depletion syn...

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Dades bibliogràfiques
Publicat a:Nucleic Acids Res
Autors principals: Fernández-Millán, Pablo, Lázaro, Melisa, Cansız-Arda, Şirin, Gerhold, Joachim M., Rajala, Nina, Schmitz, Claus-A., Silva-Espiña, Cristina, Gil, David, Bernadó, Pau, Valle, Mikel, Spelbrink, Johannes N., Solà, Maria
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2015
Matèries:
Structural Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4417153/
https://ncbi.nlm.nih.gov/pubmed/25824949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv189
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