Efficient manipulation of the human adenovirus genome as an infectious yeast artificial chromosome clone.

A yeast artificial chromosome (YAC) containing a complete human adenovirus type 2 genome was constructed, and viral DNA derived from the YAC was shown to be infectious upon introduction into mammalian cells. The adenovirus YAC could be manipulated efficiently using homologous recombination-based met...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Ketner, G, Spencer, F, Tugendreich, S, Connelly, C, Hieter, P
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1994
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC44163/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8016135/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.13.6186
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