Efficient manipulation of the human adenovirus genome as an infectious yeast artificial chromosome clone.
A yeast artificial chromosome (YAC) containing a complete human adenovirus type 2 genome was constructed, and viral DNA derived from the YAC was shown to be infectious upon introduction into mammalian cells. The adenovirus YAC could be manipulated efficiently using homologous recombination-based met...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1994
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC44163/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8016135/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.13.6186 |
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